Established in 1982, the heart transplant program at Baylor St. Luke’s Medical Center is one of the most experienced programs in the world. Dr. Denton Cooley and his team performed the first successful heart transplant in the U.S.A. in 1968 at this hospital, and later implanted the first artificial heart.

Our team of specialized heart failure cardiologists and nurses are here to provide you with expert and comprehensive care across the heart failure disease spectrum. We work collaboratively to integrate all aspects of care, from medication optimization and symptom management to education on disease processes, nutrition, and physical activity.

As one of the nation's most renowned academic institutions, we are dedicated to advancing heart failure treatment through innovation and research. Our clinical trials guide the future of advanced heart failure care, ensuring that our patients receive the most effective treatments available.

If you are facing end-stage heart disease, our Heart Transplant Program offers renewed hope. As part of the Baylor St. Luke's Medical Center Transplant Institute, we provide combined heart-kidney, heart-liver, and heart-lung transplants to eligible patients with end-stage heart failure and multisystem organ involvement.

At the Advanced Heart Failure, LVAD, and Heart Transplant Program, our goal is to optimize outcomes and improve your heart health. Contact us today to schedule a consultation with one of our specialists and learn more about the comprehensive care we provide.

Baylor St. Luke’s Medical Center, together with Baylor College of Medicine—one of the top medical schools in the country—has an unparalleled level of research capabilities and collaboration that paves the way for even more revolutionary discoveries. Additionally, U.S. News & World Report recently recognized Baylor St. Luke’s Medical Center as one of the best hospitals in the country for cardiology and heart surgery. 

• We were ranked #13 in the nation by U.S. News and World Report's Best Hospital Rankings in 2021-2022 for Cardiology and Heart Surgery and #1 in Houston, Texas. 
• Over 36 years, our team has performed over 1600 heart transplants and over 1500 VADs (ventricular assist devices). 
• Our program is part of the Adult Transplant Center of Excellence through Aetna, Blue Cross Blue Shield, Optum Health, and Kelsey Seybold.

• Heart failure with reduced ejection fraction 

• Heart failure with preserved ejection fraction 

• Pulmonary hypertension 

• Hypertensive heart disease

• Amyloid heart disease 

• Sarcoid heart disease 

• Ischemic Cardiomyopathy

• Hypertrophic cardiomyopathy 

• Inherited (genetic) cardiomyopathies 

• Adult congenital heart disease 

• Arrhythmogenic right ventricular cardiomyopathy 

• Coronary Heart disease

• Heart valve disease 

• Heart rhythm disorders 

• Cardiogenic shock 

• Heart transplantation, including multiorgan transplantation

• Ventricular assist devices

• Temporary mechanical circulatory support

• Extracorporeal membrane oxygenation (ECMO) support

• Percutaneous and surgical valve replacement

• Complex coronary angioplasty and stenting

• Coronary artery bypass grafting (CABG surgery)

• Minimally invasive cardiac surgery

• Myocardial biopsy

• Pulmonary artery pressure sensor device implantation

• Remote cardiac monitoring

• Cardiac contractility modulation

• Genetic testing

• Personalized medical therapy for heart failure